This page was last updated on December 21st, 2021 at 07:37 pm
AutoDock CrankPep or ADCP is an AutoDock docking engine specialized for docking peptides. It combines technology form the protein folding filed with an efficient representation of a rigid receptor as affinity grids to fold the peptide in the context of the energy landscape created by the receptor. A Monte-Carlo search is used to fold the peptide while concurrently optimizing the interaction between the peptide and the receptor molecule, yielding docked peptides. The program can dock peptides provides as 3D structures in PDB files or from a sequence string. It has been show to successfully re-dock peptides with up to 20 amino acids in length.