CellPAINT: Digital Illustration from Atoms to Cells

With CellPAINT, you can create dynamic illustrations of the inner molecular structure of viruses and living cells. CellPAINT pictures are based on experimental results from many different laboratories. The size and shape of each molecule is based on atomic structures determined by x-ray crystallography, NMR spectroscopy and electron microscopy, and key interactions, such as the embedding of proteins in membranes, are enforced as you create your pictures.

Our new release, CellPAINT-2.0, is now available. It allows you to import new molecules into the painting palette, and adds many options for refining your molecular paintings. The web version is available below, and you can download a stand-alone version from SourceForge.

Please note: this is new software, so we are actively looking for people to test the program, share what they have created, and to give us feedback on usability and problems. There are a few Frequently-Asked Questions on the Documentation page. If you’d like to make a bug report, please use the “Tickets” at the SourceForge page.

Click here for a tutorial and documentation for CellPAINT-2.0.

Previous versions, such as CellPAINT-coronavirus, are available from the side menu.

The program is being developed by Adam Gardner, Ludovic Autin, Arthur Olson and David Goodsell, with support from the US National Institutes of Health. Thanks also to Martina Maritan for scientific support, and Melanie Stegman, Brett Barbaro and other members of the CCSB team for help with testing and usability analysis.

Our first paper describing CellPAINT is available on PubMedCentral PMC6456043.

Tell us what you think!

CellPAINT is currently in active development, and we are looking for testers. The software still has a few idiosyncracies, so please be prepared to restart the programs if you encounter problems. We are looking for feedback on several general questions:

Were you able to create the scenes that you wanted to make?
Will this type of program be useful in your own work?
Are there any features that you would like to see added?

Please send your impressions to David Goodsell at goodsell@scripps.edu.